The pharmacological studies on 2-amino-6-hy-droxy-6-methyl-heptane (A. H. O.)
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چکیده
منابع مشابه
SYNTHESIS OF 8-HYDROXY-6-METHOXY- 3-UNDECYLISOCOUMARIN AND 2-HY DROXY - 4-METHOXY-6-(2-OXOTRIDECYL) BENZOIC ACID
Straightforward conversion of (+)-6,8-dimethoxy-3,4-dihydro-3- undecylisocoumarin (3) to the title isocoumarin was carried out. Hydrolytic ring opening of (3) afforded the hydroxy acid (4) which was immediately oxidized to keto acid (5) using chromic acid, Cyclodehydration of (5) afforded the 6,8- dimethoxy-3-undecylisocoumarin (6) which on selective demethylation of 8- methoxy group furni...
متن کاملMethyl 6-amino-6-oxohexanoate
The title compound, C(7)H(13)NO(3), adopts an approximately planar conformation. The torsion angles in the aliphatic chain between the carbonyl group C atoms range from 172.97 (14) to 179.38 (14)° and the r.m.s. deviation of all non-H atoms is 0.059 Å. The crystal packing is dominated by two strong N-H⋯O hydrogen bonds involving the amide groups and forming R(2) (2)(8) rings and C(4) chains. Ov...
متن کاملsynthesis of 8-hydroxy-6-methoxy- 3-undecylisocoumarin and 2-hy droxy - 4-methoxy-6-(2-oxotridecyl) benzoic acid
straightforward conversion of (+)-6,8-dimethoxy-3,4-dihydro-3- undecylisocoumarin (3) to the title isocoumarin was carried out. hydrolytic ring opening of (3) afforded the hydroxy acid (4) which was immediately oxidized to keto acid (5) using chromic acid, cyclodehydration of (5) afforded the 6,8- dimethoxy-3-undecylisocoumarin (6) which on selective demethylation of 8- methoxy group furnished ...
متن کاملCrystal structure of methyl 2-(7-hy-droxy-2-oxo-2H-chromen-4-yl)acetate.
In the title coumarin derivative, C12H10O5, the fused ring system is almost planar (r.m.s deviation = 0.016 Å). The Car-C-C=O torsion angle of the side chain is -8.4 (2)° In the crystal, mol-ecules are linked by O-H⋯O hydrogen bonds, generating C(8) chains propagating in the [100] direction. The chains are cross-linked by weak C-H⋯O inter-actions, thereby generating undulating (001) sheets.
متن کامل2-Amino-6-methyl-1,3-benzothiazole–decanedioic acid (2/1)
Co-crystallization of 2-amino-6-methyl-1,3--benzothia-zole with deca-nedioic acid under hydro-thermal conditions afforded the title 2:1 co-crystal, 2C(8)H(8)N(2)S·C(10)H(18)O(4). The deca-nedioic acid mol-ecule is located on an inversion centre. In the crystal, inter-molecular N-H⋯O and O-H⋯O hydrogen bonds connect the components into a two-dimensional wave-like layer structure extending parall...
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ژورنال
عنوان ژورنال: Folia Pharmacologica Japonica
سال: 1961
ISSN: 0015-5691,1347-8397
DOI: 10.1254/fpj.57.399